Organization of the Manuscript

Organize submitted manuscripts as follows:

Cover Letter, Title Page, Abstract, Introduction, Materials and Methods, Results, Discussion, Acknowledgments, References, Figure Legends, Tables, and Figures.

Cover Letter
Please identify the name, address, phone number, fax number, and e-mail address of the corresponding author. The cover letter should also specify the category of manuscript (such as Short Communication). Where appropriate, the cover letter also should indicate that the authors are willing to pay the extra costs involved in publishing any color photographs in the text. Please contact the editorial office for proce quotes.

Title Page
The title page should contain 1) full title; 2) authors' names; 3) names of institutions in which the work was done; 4) research grant support as a footnote to the title; 5) name, address, phone number, fax number, and email address of the corresponsing author; 6) a list of key words (three words are best, but up to five are acceptable); and 7) a running head/short title.

Abstract
The abstract of 200 words or less should state the rationale, objectives, findings, and conclusions of the study. Do not include a summary at the end of the discussion.

Acknowledgements
Grant support should not be included in the acknowledgements, but should be cited as a footnote to the title.

References
Cite all references in the text in consecutive, numerical order, using arabic numerals in square brackets. at the end of the article according to the order of citation in the text. Personal communications, unpublished observations, and papers in press cannot be included in the reference seciton, although they may be cited in the text and explained in parentheses. Abbreviate the names of journals according to those used in the latest edition of Index Medicus, Superintendent of Documents, U.S. Government Printing Office, Washington, DC 20402. References to abstracts and letters must be appropriately identified.

Please use the following form for references:

9. Singer JW, Charbord P, Keating A, et al. Simian virus 40-transformed adherent cells from human long-term marrow cultures: cloned cell lines produce cells with stromal and hematopoietic characteristics. Biol Blood Marrow Transplant. 1995;7:464-469.

10. Cone RD, Williams DA, Davies TF: Establishment of differentiated cell lines using oncogene-containing retroviral vectors. In: Glunzman Y, Hughes SH, eds. Viral Vectors. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press; 1993:34-39

Abbreviations
Abbreviations should be defined at their first use and applied consistently throughout the article. Do not use nonstandard abbreviations. Give the chemical name of a compound after the first use of the trivial name. The trivial name may follow throughout the article. Abbreviate units of measure only when used with numbers.

Units
Use the international System of Units (SI) consistently in the text, figures, and tables. Note that the abbreviation for liter is L; that for mole is mol. Units and terms commonly used in the journal without definition include the following: mass: kg, g, mg, ug, ng, pg; mass concentration: kg/L, g/L, mg/L, ug/L; substance concentration: mol/L, mmol/L, nmol/L, umol/L; temperature: °C; density: kg/L; absorbance: A; international unit of enzyme activity: M/s (katal is also acceptable); units of peptide hormones and vitamins: IU; statistical measures: P, r, R2.

Tables
Each table should be printed or typed on a separate page, appropriately numbered and cited in numerical order in the text. Legends giving sufficient explanation to make the data intelligible without reference to the text must be typed on the same page.

Figures and Figure Legends
Figures must be cited in the text in numerical order using arabic numerals. Submit three complete sets of unmounted clear, glossy, black and white photographs or negatives. For line drawings, either a single set of photographs with two sets of copies or three sets of high-quality laser figures are acceptable. Do not write on either the front or back of photographs. Do not mount the figures, fasten them with paper clips, or store them in clasp envelopes where the clasp can damage the photo in the mail. Figures submitted on floppy disk must be accompanied by a high-quality printout in case the file is not readable; please clearly mark the disk with the author's name, the file name, and the file format. Figure legends should be double-spaced on a separate sheet, and should include a brief title and a concise explanation of each figure. The cost of publishing color photographs will be borne by the authors.

Proofreading
Authors of accepted manuscripts will receive galley proofs directly from the publisher and are responsible for proofreading. Except for correcting typesetting errors, authors may be charged for extensive alterations. Galley proofs should be returned within 48 hours to avoid delay in publication.